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METROGEL-VAGINAL affords nominal peak serum stages and systemic exposure (AUCs) of metronidazole in comparison to five hundred mg oral metronidazole dosing. Despite the fact that these reduced amounts of exposure are more unlikely to provide the popular reactions viewed with oral metronidazole, the potential of these along with other reactions can not be excluded presently.

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Psychotic reactions are documented in alcoholic individuals who were being employing oral metronidazole and disulfiram concurrently. Metronidazole vaginal gel really should not be administered to sufferers who've taken disulfiram inside the past two weeks.